Exelixis: The Double Backbone Potential Of CABOMETYX And Zanzalintinib

Exelixis is positioned to evolve into a multi-franchise oncology company, anchored by CABOMETYX and the emerging zanzalintinib. CABOMETYX remains a durable cash generator, while zanzalintinib is expected to drive significant growth, with peak sales estimates of $5B by 2033. 2026 guidance projects $2.52B–$2.62B in revenue, excluding potential zanzalintinib contributions, as the company maintains robust R&D and share repurchases.